Bacteremia in Blood or Marrow Transplantation Patients: Clinical Risk Factors for Infection and Emerging Antibiotic Resistance Allison M. Bock, Qing.

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Presentation transcript:

Bacteremia in Blood or Marrow Transplantation Patients: Clinical Risk Factors for Infection and Emerging Antibiotic Resistance Allison M. Bock, Qing Cao, Patricia Ferrieri, Jo-Anne H. Young, Daniel J. Weisdorf Biology of Blood and Marrow Transplantation Volume 19, Issue 1, Pages 102-108 (January 2013) DOI: 10.1016/j.bbmt.2012.08.016 Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Cumulative incidence of bacteremia by 100 days posttransplantation comparing autologous and allogeneic transplantations and different allogeneic donor types. Three infection groups are shown (all bacteremia, all excluding coagulase-negative Staphylococcus, and Gram-negative bacteria) (left panels). Among allogeneic transplantations, the incidence of bacteremia is similar in each infection group (right panels). Allo, allogeneic transplantation; Auto, autologous transplantation; RD, related donor; URD, unrelated donor, blood, or marrow cell source; UCB, umbilical cord blood. Biology of Blood and Marrow Transplantation 2013 19, 102-108DOI: (10.1016/j.bbmt.2012.08.016) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 The in vitro antibiotic sensitivity of P. aeruginosa (A), E. coli (B), and K. pneumoniae (C) blood isolates from hospital-wide patients and patients who underwent BMT between 2005 and 2010. Diamond (♦) denotes statistically significant sensitivity differences (P < .05) between hospital and bone marrow transplantation (BMT) blood isolates. Biology of Blood and Marrow Transplantation 2013 19, 102-108DOI: (10.1016/j.bbmt.2012.08.016) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 The in vitro antibiotic sensitivity of coagulase-negative Staphylococcus (coagulase-negative Staphylococcus) (A) and Enterococcus (including E. faecium and group D Enterococcus) (B) blood isolates from hospital-wide patients and patients who underwent bone marrow transplantation (BMT) between 2005 and 2010. Diamond (♦) denotes statistically significant sensitivity differences (P < .05) between hospital and BMT blood isolates Biology of Blood and Marrow Transplantation 2013 19, 102-108DOI: (10.1016/j.bbmt.2012.08.016) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions