MicroRNA expression profiles of esophageal cancer

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Presentation transcript:

MicroRNA expression profiles of esophageal cancer Andrew Feber, PhD, Liqiang Xi, MD, James D. Luketich, MD, Arjun Pennathur, MD, Rodney J. Landreneau, MD, Maoxin Wu, MD, Scott J. Swanson, MD, Tony E. Godfrey, PhD, Virginia R. Litle, MD The Journal of Thoracic and Cardiovascular Surgery Volume 135, Issue 2, Pages 255-260 (February 2008) DOI: 10.1016/j.jtcvs.2007.08.055 Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 MicroRNA expression patterns distinguish esophageal adenocarcinoma (AC), squamous cell carcinoma (SCC), normal squamous epithelium (NSE), Barrett esophagus (BE), and high-grade dysplasia (HGD). A, Unsupervised hierarchic clustering of esophageal specimens with all expressed miRNAs. Linked samples (1882/1881 and MS629/MS628) were obtained from the same patient. B, Principal component analysis mapping based on 14 miRNAs that exhibit differential expression between adenocarcinoma (red triangle), squamous cell carcinoma (yellow circle), normal squamous epithelium (purple hexagon), Barrett esophagus (blue square), and high-grade dysplasia (green diamond). The Journal of Thoracic and Cardiovascular Surgery 2008 135, 255-260DOI: (10.1016/j.jtcvs.2007.08.055) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions