Left ventricular hypertrophy in renal failure

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Left ventricular hypertrophy in renal failure Kerstin Amann, Ivan Rychlík, Gabriel Miltenberger-Milteny, Eberhard Ritz  Kidney International  Volume 54, Pages S78-S85 (December 1998) DOI: 10.1046/j.1523-1755.1998.06818.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Schema of the genesis (top) and sequelae (bottom) of left ventricular hypertrophy in renal failure. Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Heart of a patient with chronic renal failure. Note hypertrophy of cardiomyocytes and diffuse interstitial fibrosis (HE stain, paraffin section; magnification 1:250). Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Expression of endothelin 1 in the myocardial interstitium of a patient with renal failure of 20 years duration. (Immunohistochemistry, paraffin section; magnification 1:150). Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 (A) Capillary density in the heart.(Semithin section; magnification A-C 1:500). (b) Reduced capillary density in the heart of a subtotally nephrectomized rat with renal failure of 12 weeks duration. (C) Normalization of capillary density in the heart of a subtotally nephrectomized rat treated with the selective ET-1 receptor blocker LU 135252. Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 (A) Capillary density in the heart.(Semithin section; magnification A-C 1:500). (b) Reduced capillary density in the heart of a subtotally nephrectomized rat with renal failure of 12 weeks duration. (C) Normalization of capillary density in the heart of a subtotally nephrectomized rat treated with the selective ET-1 receptor blocker LU 135252. Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 5 (A) Normal aortic architecture in a sham operated control animal. (Semithin section; magnification A-B, 1:700). (B) Wall thickening of the aorta with an increase in cell number and extracellular matrix content in a subtotally nephrectomized rat with renal failure of eight weeks duration. Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, S78-S85DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, S78-S85DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, S78-S85DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, S78-S85DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, S78-S85DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, S78-S85DOI: (10.1046/j.1523-1755.1998.06818.x) Copyright © 1998 International Society of Nephrology Terms and Conditions