PHYTOCHEMICALS -VILLAIN OR HERO- Marvin Perkins

PHYTOCHEMICALS - VILLAIN OR HERO WHAT IS DISEASE? A pathological condition of a part of an organ, or system of an organism resulting from various causes, such as infection, genetic defect, or environmental stress, and characterized by an identifiable group of signs or symptoms. Did you know that every thing we eat and drink produces a haematological and histological effect on our body. That is to say the foods we eat affect our blood and blood-forming organs (such as the marrow of certain bones, the liver, thymus, and the spleen) and the microscopic cells, which form tissues that make up the organs in our body in a positive or negative way. This brings me to my point. Disease starts when there is a surplus or deficiency of certain nutritive or non-nutritive substances in the human body.

PHYTOCHEMICALS AND YOUR HEALTH

PHYTOCHEMICALS - VILLAIN OR HERO What Are Phytochemicals? Phytochemicals are plant chemicals that derive only from plant-based foods. They are not necessarily nutritive, however they have the ability to compete with our own body chemicals to offset disrupting changes and maintain metabolic equilibrium.

PHYTOCHEMICALS - VILLAIN OR HERO Phytoestrogen Deficiency: A major cause of modern disease What are Phytoestrogens? Phytoestrogens are natural plant molecules similar in shape and size to the human body's estrogen, but not identical. This slight difference means they do not carry the negative effects of mammalian estrogens.

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO Nature's Designer Estrogens An imbalance in estrogen is strongly linked to many major Western diseases, including heart disease and cancer. Overtime, excess estrogen in the body promote the growth of CANCER, such as prostate and breast cancer.

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO Normal mammalian estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for post menopausal women, and in hormone replacement therapy for trans women. Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors which in turn modulate the expression of many genes.

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO Estrogen receptor-positive breast cancer patients are commonly treated with the anti-estrogen tamoxifen, which gives a 50% reduction in recurrence. Here, we describe that inactivation of the estrogen receptor by anti-estrogens.

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO Due to tamoxifen inability to bind with the coactivators after a while the breast cancer cells become resistant to tamoxifen, and cause rapid conformational changes in the estrogen receptor by protein kinase A. This modification converts the antagonist tamoxifen into an agonist, reversing its intended effect on tumor cell growth. In other words, instead of stopping the growth and spread of the cancer it fosters its growth.

PHYTOCHEMICALS - VILLAIN OR HERO Numerous vitro and in-vitro research has shown that phytoestrogens such as Lignan, Genistein and Daidzein (soy isoflavones) are capable of binding to estrogen receptors (ER) to down-regulate the harmful effects of mammalian estrogen when levels are high, or to exert only half the receptor-dependent transcriptional pro-estrogenic effect to up-regulate normal mammalian oestrogen when levels are low.

PHYTOCHEMICALS - VILLAIN OR HERO However, it is to the beta receptors that plant oestrogens normally show a greater affinity when binding to oestrogen receptors. Conversely, normal oestrogenic hormone is not selective; it binds to both alpha and beta oestrogen receptors without showing preference. However, the selectiveness shown by the plant oestrogen such as lignan, genistein, daidzein, and coumestrol when binding to a beta oestrogen receptor is an innate chemical reaction that serves to boost and regulate normal mammalian oestrogenic levels and activity in the body (especially in women); to stimulate the growth of healthy osteoblast, a cell from which bone develop by building calcium into the bones, and at the same time, suppress the growth and proliferation of certain cells called osteoclast, which takes calcium from the bones, thus prevent inflammatory bone loss.

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO Rich in Genistein and Lignan Flax Seed

PHYTOCHEMICALS - VILLAIN OR HERO Rich in Lignan Sesame Seed

PHYTOCHEMICALS - VILLAIN OR HERO Rich in Genistein and Daidzein

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO All legumes, and especially Soy, contain high concentration of isoflavones, phytosterols, and other phytochemicals, whereas lignans are the primary source of phytoestrogens found in nuts and oilseeds (e.g. flax and sesame seeds). Numerous in-vitro (laboratory) test proves that the phytoestrogen present in soy and flax seed act as cytostatics, that is to say, they stop the in-vitro development of cancerous cells. Even more interesting to note is that within the human body phytoestrogens act the same way they do in-vitro.

PHYTOCHEMICALS - VILLAIN OR HERO Phytoestrogen is Good For: Breast Cancer Prostate and other cancers Heart disease and Stroke Osteoporosis Menopausal symptoms Brain diseases linked with aging: Alzheimer’s and Dementia Alcoholism Inflammatory diseases like Rheumatoid Arthritis Reduce high cholesterol

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO

PHYTOCHEMICALS - VILLAIN OR HERO