Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: a large case–control study using electronic records by Elizabeth.

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Presentation transcript:

Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: a large case–control study using electronic records by Elizabeth A Shephard, Richard D Neal, Peter Rose, Fiona M Walter, Emma J Litt, and William T Hamilton BJGP Volume 65(631):e106-e113 January 26, 2015 ©2015 by British Journal of General Practice

Application of exclusion criteria. Elizabeth A Shephard et al. Br J Gen Pract 2015;65:e106-e113 ©2015 by British Journal of General Practice

Positive predictive values for myeloma symptoms in patients aged ≥60 years, for single and paired features. Positive predictive values for myeloma symptoms in patients aged ≥60 years, for single and paired features. The positive predictive value (PPV) is shown on the first line of each cell with the 95% confidence intervals (CIs) shown underneath. PPVs were not calculated if <5 cases had the feature. Where <10 cases or controls had the combined features, CIs were omitted. Elizabeth A Shephard et al. Br J Gen Pract 2015;65:e106-e113 ©2015 by British Journal of General Practice

Positive predictive values (PPVs) for myeloma blood tests with symptoms in patients aged ≥60 years: risk estimate for single investigations and paired with symptoms. Positive predictive values (PPVs) for myeloma blood tests with symptoms in patients aged ≥60 years: risk estimate for single investigations and paired with symptoms. The PPV is shown on the first line of each cell with the 95% confidence intervals (CIs) shown underneath. PPVs were not calculated if <5 cases had the feature. Where <10 cases or controls had the combined features, CIs were omitted. The yellow shaded cells indicate a PPV of 1.0–1.9%; orange cells 2.0–4.9% and red cells of ≥5%. MCV = mean corpuscular volume. Elizabeth A Shephard et al. Br J Gen Pract 2015;65:e106-e113 ©2015 by British Journal of General Practice