Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption.

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Presentation transcript:

Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption variables  J.M. Otto, J.O.M. Plumb, D. Wakeham, E. Clissold, L. Loughney, W. Schmidt, H.E. Montgomery, M.P.W. Grocott, T. Richards  British Journal of Anaesthesia  Volume 118, Issue 5, Pages 747-754 (May 2017) DOI: 10.1093/bja/aew445 Copyright © 2017 The Author(s) Terms and Conditions

Fig 1 Equations to calculate total haemoglobin mass, blood, erythrocyte and plasma volumes. CO, carbon monoxide; %COHb, percent carboxyhaemoglobin; [Hb], haemoglobin concentration; Hct, haematocrit; BV, blood volume; EV, erythrocyte volume; PV, plasma volume; lung residual volume, 1500 ml in men, 1200 ml in women; alveolar ventilation, 5000 ml min−1. British Journal of Anaesthesia 2017 118, 747-754DOI: (10.1093/bja/aew445) Copyright © 2017 The Author(s) Terms and Conditions

Fig 2 Unadjusted relationship between haematological variables and exertional oxygen consumption. Relationship of V ˙ O 2 peak (in millilitres per kilogram per minute) to tHb-mass (in grams per kilogram) (A) and [Hb] (in grams per litre) (C) in 42 patients. Relationship of AT to tHb-mass (in grams per kilogram) (B) and [Hb] (in grams per litre) (D) in 39 patients. AT, anaerobic threshold; [Hb], haemoglobin concentration; tHb-mass, total haemoglobin mass; V ˙ O 2 peak , peak oxygen oxygen consumption. British Journal of Anaesthesia 2017 118, 747-754DOI: (10.1093/bja/aew445) Copyright © 2017 The Author(s) Terms and Conditions