Volume 126, Issue 1, Pages (January 2004)

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Presentation transcript:

Volume 126, Issue 1, Pages 91-101 (January 2004) Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine- resistant chronic hepatitis B1 Marion G. Peters, H.W. Hann, Paul Martin, E.Jenny Heathcote, P. Buggisch, R. Rubin, M. Bourliere, K. Kowdley, C. Trepo, D.F. Gray, M. Sullivan, K. Kleber, R. Ebrahimi, S. Xiong, Carol L. Brosgart Gastroenterology Volume 126, Issue 1, Pages 91-101 (January 2004) DOI: 10.1053/j.gastro.2003.10.051

Figure 1 Median log change in serum HBV DNA levels. This figure shows an initial rapid decrease at 4 weeks in both the adefovir dipivoxil and adefovir dipivoxil/lamivudine combination groups with continued reduction over 48 weeks. Gastroenterology 2004 126, 91-101DOI: (10.1053/j.gastro.2003.10.051)

Figure 2 The percentage of patients with normal ALT levels during monthly evaluations. By 24 weeks, 30% of patients receiving adefovir dipivoxil and adefovir dipivoxil/lamivudine had normal ALT levels; these percentages increased steadily thereafter. Gastroenterology 2004 126, 91-101DOI: (10.1053/j.gastro.2003.10.051)