Lower-Than-Expected Linkage Disequilibrium between Tightly Linked Markers in Humans Suggests a Role for Gene Conversion Kristin Ardlie, Shau Neen Liu-Cordero,

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Lower-Than-Expected Linkage Disequilibrium between Tightly Linked Markers in Humans Suggests a Role for Gene Conversion Kristin Ardlie, Shau Neen Liu-Cordero, Michael A. Eberle, Mark Daly, Jeff Barrett, Ellen Winchester, Eric S. Lander, Leonid Kruglyak The American Journal of Human Genetics Volume 69, Issue 3, Pages 582-589 (September 2001) DOI: 10.1086/323251 Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 1 Expected number of obligate recombination events (RM) as a function of population recombination parameter 4Nr. Dashed line indicates the observed value of ([a-z]+)M=7. Each blackened circle is an average over 1,000 simulated replicates of the data. Vertical bars show the values that fall at 2.5%–97.5% of the simulated distribution. The American Journal of Human Genetics 2001 69, 582-589DOI: (10.1086/323251) Copyright © 2001 The American Society of Human Genetics Terms and Conditions