Comparative in vitro pharmacodynamics of BO-2727, meropenem and imipenem against Gram-positive and Gram-negative bacteria Inga Odenholt, Elisabeth Löwdin,

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Presentation transcript:

Comparative in vitro pharmacodynamics of BO-2727, meropenem and imipenem against Gram-positive and Gram-negative bacteria Inga Odenholt, Elisabeth Löwdin, Otto Cars Clinical Microbiology and Infection Volume 3, Issue 1, Pages 73-81 (February 1997) DOI: 10.1111/j.1469-0691.1997.tb00254.x Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Killing curves of imipenem, meropenem and BO-2727 at a concentration corresponding to that reached in serum after 1 h against Staphylococcus aureus. Mean of three experiments. Clinical Microbiology and Infection 1997 3, 73-81DOI: (10.1111/j.1469-0691.1997.tb00254.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Killing curves of BO-2727 at different concentrations against Escherichia coli ATCC 25922. Mean of three experiments. Clinical Microbiology and Infection 1997 3, 73-81DOI: (10.1111/j.1469-0691.1997.tb00254.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Killing curves of imipenem, meropenem and BO-2727 against non-growing Escherichia coli ATCC 25922. Mean of three experiments. Clinical Microbiology and Infection 1997 3, 73-81DOI: (10.1111/j.1469-0691.1997.tb00254.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions