Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass.

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Presentation transcript:

Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting Bruno K. Podesser, MDa (by invitation), Severin Schwarzacher, MDb (by invitation), Werner Zwoelfer, MDa (by invitation), Thomas M. Binder, MDb (by invitation), Ernst Wolner, MDa, Rainald Seitelberger, MDa (by invitation) The Journal of Thoracic and Cardiovascular Surgery Volume 110, Issue 5, Pages 1461-1469 (November 1995) DOI: 10.1016/S0022-5223(95)70069-2 Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 1 Perioperative changes in heart rate. pOP, Preoperative; 1-24h mark the hours after opening of the aortic crossclamp. Data are given as mean ± standard deviation. Values differ significantly from that for nifedipine-metoprolol group (*p < 0.05, **p < 0.01). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1461-1469DOI: (10.1016/S0022-5223(95)70069-2) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 Perioperative serum creatine kinase-MB levels before the operation (pOP) and for 36 hours after opening of the aortic crossclamp. MB, MB isoenzyme of creatine kinase; Data are given as mean ± standard deviation. Value differs significantly from that for nifedipine-metoprolol group (*p < 0.05). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1461-1469DOI: (10.1016/S0022-5223(95)70069-2) Copyright © 1995 Mosby, Inc. Terms and Conditions