Gregory Piazza et al. JCIN 2015;8:

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Ultrasound Assisted Thrombolysis for Massive and Submassive Pulmonary Embolism Scott M Lilly, MD PhD Interventional Cardiology Fellows School August 15.

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Gregory Piazza et al. JCIN 2015;8:1382-1392 Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism A total of 150 patients with computed tomography (CT)-confirmed pulmonary embolism (PE), symptoms for 14 days or less, and a right ventricular (RV)/left ventricular (LV) diameter ratio of at least 0.9 underwent ultrasound-facilitated, catheter-directed, low-dose fibrinolysis according to a standardized protocol. Ultrasound-facilitated, catheter-directed, low-dose fibrinolysis for acute massive and submassive pulmonary embolism (PE) improved RV function, decreased pulmonary hypertension, and minimized intracranial hemorrhage. PA = pulmonary artery; tPA = tissue plasminogen. Gregory Piazza et al. JCIN 2015;8:1382-1392 2015 American College of Cardiology Foundation