A Practical Approach to the Detection of Prognostically Significant Genomic Aberrations in Multiple Myeloma Zhong Chen, Bonnie Issa, Shiang Huang, Emily.

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Presentation transcript:

A Practical Approach to the Detection of Prognostically Significant Genomic Aberrations in Multiple Myeloma Zhong Chen, Bonnie Issa, Shiang Huang, Emily Aston, Jia Xu, Margaret Yu, Arthur R. Brothman, Martha Glenn The Journal of Molecular Diagnostics Volume 7, Issue 5, Pages 560-565 (November 2005) DOI: 10.1016/S1525-1578(10)60588-0 Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 One cell with two RB-1 orange signals representing a normal cell (A) and two cells each with one orange signal indicating the RB-1 deletion (B and C). The Journal of Molecular Diagnostics 2005 7, 560-565DOI: (10.1016/S1525-1578(10)60588-0) Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 2 One cell with two IgH orange/green (yellow) fusion signals representing a normal cell (A) and two cells each with an one orange, one green, and one orange/green (yellow) fusion signal pattern indicating the presence of an IgH rearrangement (B and C). The Journal of Molecular Diagnostics 2005 7, 560-565DOI: (10.1016/S1525-1578(10)60588-0) Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions