Regulation of the Cell Cycle

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Regulating the Cell Cycle
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Presentation transcript:

Regulation of the Cell Cycle

Learning Objectives Describe how the cell cycle is regulated Explain how cancer cells are different from normal cells

Regulating the Cell Cycle Not all cells move through the cell cycle at the same rate. Cells of the skin and digestive tract divide rapidly. Adult muscle and nerve cells do not divide.

How is the cell cycle regulated? Internal Regulators: Proteins that respond to events inside the cell. Ex. Cyclin External Regulators: Proteins that respond to events outside the cell. Ex. Growth Factors

Uncontrolled Cell Growth Cancer - a disorder in which some of the body’s own cells lose the ability to control growth.

Characteristics of Cancer Divide uncontrollably Form masses called tumors Damage surrounding tissue Break loose from tumors and spread throughout the body - Metastasis

Causes of Cancer Genetics/Heredity: Mutated Genes Environmental Factors: Smoking/Tobacco Carcinogens Sun/UV Radiation Diet/Physical Activity

Treatments for Cancer Surgery Radiation therapy Chemotherapy

Cancer Facts and Figures Cancer is a leading cause of death worldwide. Deaths caused by cancer this year: 7,602,215

YouTube Video Cell Cycle and Cancer Amoeba Sisters

Cancer: Unregulated Cell Division YouTube Video Cancer: Unregulated Cell Division

Stop Here

Stem Cells Stem cells - unspecialized cells that have the potential to become a variety of cell types. Every cell in an organism was produced by mitosis from stem cells.