Global Edgetic Rewiring in Cancer Networks

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Global Edgetic Rewiring in Cancer Networks Yang Wang, Nidhi Sahni, Marc Vidal  Cell Systems  Volume 1, Issue 4, Pages 251-253 (October 2015) DOI: 10.1016/j.cels.2015.10.006 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Edgetic Rewiring in Cancer Networks One of the bottlenecks in cancer research is to understand how cancer variants result in tumorigenesis. One promising strategy to address this is to use global models of how edgetic mutations, which affect interactions between genes or gene products, rewire networks. Different colored boxes indicate distinct network-based profiles that are discussed in this Preview. Cell Systems 2015 1, 251-253DOI: (10.1016/j.cels.2015.10.006) Copyright © 2015 Elsevier Inc. Terms and Conditions