Detection rate for EGFR mutations in cfDNA.

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Detection rate for EGFR mutations in cfDNA. Detection rate for EGFR mutations in cfDNA. Detection rates from cfDNA for TKI-sensitive and T790M mutations are shown. Twenty samples were collected from patients with resistance to EGFR-TKI therapy (patients 1–20), and 24 from patients before EGFR-TKI therapy (patients 1, 8, 10–12, 16, 17 and 21–37). cfDNA, cell-free DNA; EGFR, epidermal growth factor receptor; TKI, tyrosine kinase inhibitor. Yoshitaka Seki et al. ESMO Open 2018;3:e000292 Copyright © European Society for Medical Oncology. All rights reserved.