Early Detection and Monitoring of Vulnerable Myocardium in Patients Receiving Chemotherapy: Is It Time to Change Tracks?  Ragavendra R. Baliga, MD, MBA 

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Early Detection and Monitoring of Vulnerable Myocardium in Patients Receiving Chemotherapy: Is It Time to Change Tracks?  Ragavendra R. Baliga, MD, MBA  Heart Failure Clinics  Volume 7, Issue 3, Pages xiii-xix (July 2011) DOI: 10.1016/j.hfc.2011.05.001 Copyright © 2011 Terms and Conditions

Fig. 1 Adjusted Kaplan-Meier estimates of survival according to the underlying cause of cardiomyopathy. Only idiopathic cardiomyopathy and cardiomyopathy caused by causes for which survival was significantly different from that in patients with idiopathic cardiomyopathy are shown. (From Felker GM, Thompson RE, Hare JM, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000;342(15):1077–84; with permission.) Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

Fig. 2 Carvedilol in anthracycline-induced cardiomyopathy. Left ventricular ejection fraction (EF) at baseline (black bars) and after chemotherapy (white bars) in carvedilol (N = 25) and control (N = 25) groups. Data expressed as mean values. (From Kalay N, Basar E, Ozdogru I, et al. Protective effects of carvedilol against anthracycline-induced cardiomyopathy. J Am Coll Cardiol 2006;48(11):2258–62; with permission.) Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

Fig. 3 Peak longitudinal strain obtained using speckle tracking during systolic contraction from 6 regions of interest that are angle independent and occur almost simultaneously in this normal patient. AVC, aortic valve closure; GS, global strain index. (From St John Sutton MG, Plappert T, Rahmouni H. Assessment of left ventricular systolic function by echocardiography. Heart Fail Clin 2009;5(2):177–90.) Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

Fig. 4 A plot out of circumferential (C), radial (R), and longitudinal (L) strains from a normal patient in whom there is the usual regional temporal coordination of contraction. (From St John Sutton MG, Plappert T, Rahmouni H. Assessment of left ventricular systolic function by echocardiography. Heart Fail Clin 2009;5(2):177–90.) Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

Ragavendra R. Baliga, MD, MBA, Consulting Editor Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

James B. Young, MD, Consulting Editor Heart Failure Clinics 2011 7, xiii-xixDOI: (10.1016/j.hfc.2011.05.001) Copyright © 2011 Terms and Conditions

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