Eung Bae Lee, MD, Tae I. n Park, MD, PhD, Sun H

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Loss of heterozygosity on the long arm of chromosome 21 in non–small cell lung cancer Eung Bae Lee, MD, Tae I.n Park, MD, PhD, Sun H.a Park, MSc, Jae Yong Park, MD, PhD The Annals of Thoracic Surgery Volume 75, Issue 5, Pages 1597-1600 (May 2003) DOI: 10.1016/S0003-4975(02)04902-0 Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Frequencies of loss of heterozygosity (LOH) detected at nine microsatellite markers on 21q. Open boxes indicate retention; diagonally striped boxes indicate noninformative cases; filled boxes indicate LOH. a = incidence is expressed by number of cases with LOH per number of informative cases. The Annals of Thoracic Surgery 2003 75, 1597-1600DOI: (10.1016/S0003-4975(02)04902-0) Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Representative autoradiograms of a case showing interstitial deletions. Loss of heterozygosity at markers D21S 1432, D21S1437, and D21S1435 and retention of heterozygosity at other markers. Arrows indicate allelic loss in tumor DNA. Numbers at bottom of radiograms represent microsatellite markers. (L = lymphocyte DNA; T = tumor DNA.) The Annals of Thoracic Surgery 2003 75, 1597-1600DOI: (10.1016/S0003-4975(02)04902-0) Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions