Swallowed Fluticasone Improves Histologic but Not Symptomatic Response of Adults With Eosinophilic Esophagitis Jeffrey A. Alexander, Kee Wook Jung, Amindra.

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Swallowed Fluticasone Improves Histologic but Not Symptomatic Response of Adults With Eosinophilic Esophagitis Jeffrey A. Alexander, Kee Wook Jung, Amindra S. Arora, Felicity Enders, David A. Katzka, Gail M. Kephardt, Hirohito Kita, Lori A. Kryzer, Yvonne Romero, Thomas C. Smyrk, Nicholas J. Talley Clinical Gastroenterology and Hepatology Volume 10, Issue 7, Pages 742-749.e1 (July 2012) DOI: 10.1016/j.cgh.2012.03.018 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 Study flow chart. BX, biopsy; EGD, esophagogastroduodenoscopy; GI, gastrointestinal. Clinical Gastroenterology and Hepatology 2012 10, 742-749.e1DOI: (10.1016/j.cgh.2012.03.018) Copyright © 2012 AGA Institute Terms and Conditions

Figure 2 (A) Pretreatment H&E stain, with a mean of 26.2 eos/hpf. (B) Pretreatment EDN stain with an intracellular score of 1.6, and an extracellular score of 3.0. The arrow points to an intact eosinophil, and the arrowhead points to extracellular EDN uptake. (C) Post-treatment H&E stain with a mean of 0 eos/hpf. (D) Post-treatment EDN stain with an intracellular score of 0.5 and an extracellular score of 0.5. Clinical Gastroenterology and Hepatology 2012 10, 742-749.e1DOI: (10.1016/j.cgh.2012.03.018) Copyright © 2012 AGA Institute Terms and Conditions

Figure 3 Erosive esophagitis. EGD, esophagogastroduodenoscopy; LA, Los Angeles; Tx, treatment. Clinical Gastroenterology and Hepatology 2012 10, 742-749.e1DOI: (10.1016/j.cgh.2012.03.018) Copyright © 2012 AGA Institute Terms and Conditions

Supplementary Figure 1 CONSORT flow diagram. Clinical Gastroenterology and Hepatology 2012 10, 742-749.e1DOI: (10.1016/j.cgh.2012.03.018) Copyright © 2012 AGA Institute Terms and Conditions