L. Menashe, K. Hirko, E. Losina, M. Kloppenburg, W. Zhang, L. Li, D. J

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Presentation transcript:

The diagnostic performance of MRI in osteoarthritis: a systematic review and meta- analysis  L. Menashe, K. Hirko, E. Losina, M. Kloppenburg, W. Zhang, L. Li, D.J. Hunter  Osteoarthritis and Cartilage  Volume 20, Issue 1, Pages 13-21 (January 2012) DOI: 10.1016/j.joca.2011.10.003 Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Flow chart of the screening process for articles included in the systematic review. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Plot showing sensitivity of MRI use in OA viewing various tissue types in the 16 studies with complete data. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Plot showing specificity of MRI use in OA viewing various tissue types in the 16 studies with complete data. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Plot of summary ROC curve comparing MRI techniques with other reference standards in the 16 studies with complete data: X-ray, clinical diagnosis, arthroscopy, histology, direct visualization, and CT scan. Diagnostic accuracy is demonstrated by plotting 1-specificity (x-axis) vs sensitivity (y-axis). The AUC is 0.804. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 5 Funnel plot of sensitivity in the 16 studies with complete data. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 6 Funnel plot of specificity in the 16 studies with complete data. Osteoarthritis and Cartilage 2012 20, 13-21DOI: (10.1016/j.joca.2011.10.003) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions