Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review

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Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review Dr Sarah Larney, PhD, Amy Peacock, PhD, Janni Leung, PhD, Samantha Colledge, BPSc, Prof Matthew Hickman, PhD, Prof Peter Vickerman, PhD, Jason Grebely, PhD, Kostyantyn V Dumchev, MD, Paul Griffiths, MSc, Lindsey Hines, PhD, Evan B Cunningham, BSc, Prof Richard P Mattick, PhD, Prof Michael Lynskey, PhD, Prof John Marsden, PhD, Prof Sir John Strang, FMedSci, Prof Louisa Degenhardt, PhD The Lancet Global Health Volume 5, Issue 12, Pages e1208-e1220 (December 2017) DOI: 10.1016/S2214-109X(17)30373-X Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

Figure 1 Study selection The diagram details searches undertaken to determine numerators used to develop estimates. For searches and methods used to determine population sizes (denominators), see Degenhardt and colleagues.4 The Lancet Global Health 2017 5, e1208-e1220DOI: (10.1016/S2214-109X(17)30373-X) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

Figure 2 Global coverage of needle and syringe programmes among people who inject drugs NSP=needle and syringe programmes. PWID=people who inject drugs. The Lancet Global Health 2017 5, e1208-e1220DOI: (10.1016/S2214-109X(17)30373-X) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

Figure 3 Global coverage of opioid substitution therapy among people who inject drugs OST=opioid substitution therapy. PWID=people who inject drugs. The Lancet Global Health 2017 5, e1208-e1220DOI: (10.1016/S2214-109X(17)30373-X) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

Figure 4 Combination coverage of needle and syringe programmes and opioid substitution therapy for people who inject drugs Includes only countries with a non-zero estimate of both NSP and OST coverage. Circle area indicates national estimate of population size of PWID. PWID=people who inject drugs. NSP=needle and syringe programmes. OST=opioid substitution therapy. The Lancet Global Health 2017 5, e1208-e1220DOI: (10.1016/S2214-109X(17)30373-X) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions