Ventilator-associated pneumonia—Understanding epidemiology and pathogenesis to guide prevention and empiric therapy  Patrick Francioli, Jean Chastre,

Slides:



Advertisements
Similar presentations
Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages
Advertisements

Laboratory diagnosis and biosafety issues of biological warfare agents
C.-S. Lee, J.-H. Lee  Clinical Microbiology and Infection 
Frequency and molecular diversity of Pseudomonas aeruginosa upon admission and during hospitalization: a prospective epidemiologic study  Dominique S.
Grepafloxacin: microbiological properties
Gut bacterial microbiota and obesity
Approach to diagnosis of infective endocarditis
The changing epidemiology of severe infections in the ICU
European perspective and update on the management of nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus after more than 10 years.
Herpes zoster in non-hospitalized children
Atypical respiratory pathogens
C.-S. Lee, J.-H. Lee  Clinical Microbiology and Infection 
J.-P. Van geertruyden  Clinical Microbiology and Infection 
Hydatid disease Clinical Microbiology and Infection
Link between intracellular pathogens and cardiovascular diseases
J. Rello, E. Afonso, T. Lisboa, M. Ricart, B. Balsera, A. Rovira, J
How to evaluate and predict the ecologic impact of antibiotics: the pharmaceutical industry view from research and development  R. Bax  Clinical Microbiology.
F. Rodríguez-Gómez, O. Cuevas, J. Anguita, P. Muñoz 
How to evaluate and predict the epidemiologic impact of antibiotic use in humans: the pharmacoepidemiologic approach  D. Guillemot  Clinical Microbiology.
In vitro activity, postantibiotic effect and human monocyte activity of grepafloxacin against Legionella species  Jacques Dubois, Claude St-Pierre  Clinical.
Holt Hanne M. , Søgaard Per , Gahrn-Hansen Bente  
Structure of grepafloxacin relative to activity and safety profile
European guidelines for diagnosis and management of patients with suspected herpes simplex encephalitis  Paul E. Klapper, Graham M. Cleator  Clinical.
The role of fourth-generation cephalosporins in the treatment of infections caused by penicillin-resistant streptococci  Keith Klugman, Fred Goldstein,
Fourth-generation cephalosporins: a review of in vitro activity, pharmacokinetics, pharmacodynamics and clinical utility  Javier Garau, Walter Wilson,
C-3′Quaternary Ammonium Cephems, a New Wave of Cephalosporins
Sofie Arens, Jan Verhaegen, Ludo Verbist 
Training for the infectious diseases speciality in Norway
G. Höffken  Clinical Microbiology and Infection 
Cephalosporins: a pharmacological update
Retrospective study of CMV retinitis in patients with AIDS
Epidemiology of opportunistic infections in AIDS patients
Laboratory diagnosis and biosafety issues of biological warfare agents
Sepsis and neutropenia induced by clozapine
Antibiotic usage and the incidence of resistance
Uncommon opportunistic fungi: new nosocomial threats
André Bryskier  Clinical Microbiology and Infection 
Levofloxacin in the treatment of ventilator-associated pneumonia
Effect of antioxidants on the immune response of Helicobacter pylori
Laboratory diagnosis of Clostridium difficile disease
Recent developments in staphylococcal scalded skin syndrome
S8 – S47 and O50 – O440 Clinical Microbiology and Infection
The practice of travel medicine in Europe
Pathogenesis of catheter-related infections: lessons for new designs
Community-acquired pneumonia: epidemiologic and clinical consideration
Grepafloxacin: pharmacokinetics and tissue penetration
Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial 
Training in infectious diseases and tropical medicine in Britain
Reducing antibiotic use in influenza: challenges and rewards
Ethan Rubinstein, Itzhak Levy  Clinical Microbiology and Infection 
Outpatient and home parenteral antibiotic therapy (OHPAT) in the UK: a consensus statement by a working party  Dilip Nathwani, Christopher Conlon  Clinical.
Statin use and clinical outcomes among pneumonia patients
Clinical Microbiology and Infection
European guidelines for diagnosis and management of patients with suspected herpes simplex encephalitis  Miles Denton, Kevin G Kerr, Fraser Lewis  Clinical.
Clinical Microbiology and Infection
Empiric therapy of bacterial infections in severe neutropenia
W. Eugene Sanders, Christine C. Sanders 
Detection of IgA and low-avidity IgG antibodies for the diagnosis of recent active toxoplasmosis  José Gutiérrez, María Rodríguez, Gonzalo Piédrola, María.
Overview of cefixime use in community-acquired infections
Sanford Chodosh  Clinical Microbiology and Infection 
The atypical pneumonias: clinical diagnosis and importance
Facilitating learning and change in physicians: Implications for a system of continuing medical education in Europe  Robert D. Fox  Clinical Microbiology.
Abstracts Clinical Microbiology and Infection
Modelling during an emergency: the 2009 H1N1 influenza pandemic
New oral cephalosporins in pediatric community-acquired infections
Javier Aznar, Hassan Safi, Maria C. Conejo, José C. Palomares 
Impact of antibiotic restrictions: the patient's perspective
Outpatient and home parenteral antibiotic therapy (OHPAT) in the UK: a consensus statement by a working party  Dilip Nathwani, Christopher Conlon  Clinical.
Fernando Baquero, John F
The future of diagnostic bacteriology
Presentation transcript:

Ventilator-associated pneumonia—Understanding epidemiology and pathogenesis to guide prevention and empiric therapy  Patrick Francioli, Jean Chastre, Martin Langer, Jose Ignacio Santos, Pramod M Shah, Antonio Torres  Clinical Microbiology and Infection  Volume 3, Pages S61-S76 (April 1997) DOI: 10.1111/j.1469-0691.1997.tb00647.x Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 1 Routes of infection in ventilator-associated pneumonia Clinical Microbiology and Infection 1997 3, S61-S76DOI: (10.1111/j.1469-0691.1997.tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 2 Effect of anti-ulcer prophylaxis on the incidence on pneumonia. With permission of Annals of Internal Medicine 64. Clinical Microbiology and Infection 1997 3, S61-S76DOI: (10.1111/j.1469-0691.1997.tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 3 Summary of reported cases of nosocomial pneumonia in mechanically-ventilated patients randomized to stress bleeding prophylaxis with sucralfate (▪) versus antacids (□) and H2 blockers (□) or H2 blockers alone (▪). Adapted from Craven et al. 72. Prevention and control of nosocomial infections. Williams & Wilkins (1990). Clinical Microbiology and Infection 1997 3, S61-S76DOI: (10.1111/j.1469-0691.1997.tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions