Cytotoxic effects of PM1 and PM2 empty particle controls and coincubation of CFZ with empty particles tested in H460 (A) and RPMI-8226 (B) cells. Cytotoxic effects of PM1 and PM2 empty particle controls and coincubation of CFZ with empty particles tested in H460 (A) and RPMI-8226 (B) cells. Results are represented as percentage of cell viability of vehicle-only control. Empty particle controls and coincubation controls were compared at 50 nM equivalent CFZ concentration in both cell lines. Data are represented as means ± S.E.M. Lin Ao et al. J Pharmacol Exp Ther 2015;355:168-173 Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics