On Viruses, Discovery, and Recognition

Slides:

Advertisements

Similar presentations

UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions Hector Rincon-Arano, Jessica Halow, Jeffrey J.

Advertisements

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry Xing Zhang, Lei Jin, Qin Fang, Wong H. Hui, Z. Hong Zhou Cell.

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics Carlos L. Arteaga, Jeffrey A. Engelman Cancer Cell Volume.

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:

Integration of Genomic Data Enables Selective Discovery of Breast Cancer Drivers Félix Sanchez-Garcia, Patricia Villagrasa, Junji Matsui, Dylan Kotliar,

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles Sandra E. Encalada, Lukasz Szpankowski, Chun-hong Xia,

HIV-1 at 25 Cell Volume 133, Issue 4, Pages (May 2008)

Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy

Jochen G. Schneider, Joseph H. Nadeau Cell Metabolism

A Prize for Cancer Prevention

Robert Koch: The Grandfather of Cloning?

Engineering a Biological Revolution

Lock and Key to Transcription: σ-DNA Interaction

Engineering a Biological Revolution

Opening the HIV Mystery Box

In This Issue Cell Volume 158, Issue 5, (August 2014)

Francis Crick: A Singular Approach to Scientific Discovery

Volume 141, Issue 2, Pages (April 2010)

Volume 129, Issue 4, Pages (May 2007)

God's Gift to Women: The Human Papillomavirus Vaccine

Monkey Research in China: Developing a Natural Resource

A New Way to Diversify Antibodies by DNA Transposition

Volume 152, Issue 1, (January 2013)

Monkey Research in China: Developing a Natural Resource

Barry Marshall 2005 Nobel Laureate in Medicine and Physiology

Better Imaging through Chemistry

Volume 130, Issue 6, (September 2007)

A Place and a Grid in the Sun

When Biology Doesn’t Add Up

Volume 131, Issue 4, Pages (November 2007)

Volume 143, Issue 6, (December 2010)

Volume 166, Issue 4, Pages (August 2016)

The Cell Biology of Genomes: Bringing the Double Helix to Life

Cells of Origin in Skin Cancer

Learning from the Uncontrollable

A Fetching Model Organism

Volume 162, Issue 6, Pages (September 2015)

Volume 163, Issue 4, (November 2015)

News Beyond Our Pages Journal of Allergy and Clinical Immunology

Volume 163, Issue 2, (October 2015)

Volume 134, Issue 6, (September 2008)

David Hubel and Torsten Wiesel

Volume 12, Issue 6, Pages (December 2007)

In This Issue Cell Volume 145, Issue 3, (April 2011)

Volume 148, Issue 1, (January 2012)

Targeting Protein Stability with a Small Molecule

Presentation transcript:

On Viruses, Discovery, and Recognition Robin A. Weiss Cell Volume 135, Issue 6, Pages 983-986 (December 2008) DOI: 10.1016/j.cell.2008.11.022 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 Viruses in the Spotlight (A) A model of a virus-like particle of the HPV vaccine in which recombinant L1 proteins assemble into pentamers, which in turn form particles (image courtesy of Mark Feinberg, Merck & Co, Inc.). (B) HIV particles (artificially colored red) budding from a CD4+ T lymphocyte (image courtesy of David Hockley and Robin A. Weiss). Cell 2008 135, 983-986DOI: (10.1016/j.cell.2008.11.022) Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 2 HPV and HIV Bring Home the Prize Shown are this year's winners of the Nobel Prize for Physiology or Medicine: (left) Harald zur Hausen of the University of Heidelberg and (right) Francoise Barré-Sinoussi and Luc Montagnier of the Pasteur Institute. (Left image courtesy of the German Cancer Research Center; right image courtesy and copyright of Institut Pasteur.) Cell 2008 135, 983-986DOI: (10.1016/j.cell.2008.11.022) Copyright © 2008 Elsevier Inc. Terms and Conditions