Chromomycin A3 staining, sperm chromatin structure assay and hyaluronic acid binding assay as predictors for assisted reproductive outcome  Martine Nijs, Eva Creemers, Annemie Cox, Kim Franssen, Mia Janssen, Elke Vanheusden, Christopher De Jonge, Willem Ombelet  Reproductive BioMedicine Online  Volume 19, Issue 5, Pages 671-684 (November 2009) DOI: 10.1016/j.rbmo.2009.07.002 Copyright © 2009 Reproductive Healthcare Ltd, Duck End Farm, Dry Drayton, Cambridge CB23 8DB, UK Terms and Conditions

Figure 1 Box plot illustration of the significant correlations of the individual sperm parameters, percent DNA fragmentation index (DFI) with good fertilization rate in IVF, percent high DNA stainability (HDS) with pregnancy rate in IVF and sperm concentration and pregnancy rate in a combined IVF/ICSI cycle. Statistical analysis was performed using the t-test. A P-value <0.05 was considered statistically significant. (a) IVF: percent DFI is significantly related to good fertilization rates in IVF (n=74, P=0.04). (b) IVF: percent HDS is significantly related to pregnancy rate (n=74, P=0.04). (c) In combined IVF/ICSI sperm concentration is significantly related to pregnancy rate (n=37, P=0.03). Reproductive BioMedicine Online 2009 19, 671-684DOI: (10.1016/j.rbmo.2009.07.002) Copyright © 2009 Reproductive Healthcare Ltd, Duck End Farm, Dry Drayton, Cambridge CB23 8DB, UK Terms and Conditions