12.4 Mutations and Gene Regulation Mutation - Change in DNA sequence Cause of Mutation - A mutagen is a factor that results in a change in DNA
12.4 Mutations and Gene Regulation What can happen as a result of a mutation? Bad mutation = disease/death Good mutation = beneficial adaptation (opposable thumbs, X-MEN) Neutral = no visible change
12.4 Mutations and Gene Regulation WE ALL UNDERGO MUTATIONS!
12.4 Mutations and Gene Regulation Types of mutations – Point Mutations Deletion – ATGCAT (delete G) ATCAT Insertion – ATGCAT (add A to the middle) ATGCAAT With Deletions and Insertions, the reading frame shifts. In some cases, the old amino acid no longer exists and a new amino acid is made. Substitution – ATGCAT (substitute A for G) ATACAT In some cases with a Substitution, a new amino acid is made and the old amino acid no longer exists.
12.4 Mutations and Gene Regulation
12.4 Mutations and Gene Regulation
12.4 Mutations and Gene Regulation
12.4 Mutations and Gene Regulation Sex cell mutations - Occurs in the sperm/egg Effects the offspring Down Syndrome can be acquired this way in addition to nondisjunction. (Ch. 11) Body cell mutations - Occurs in body cells Effects the organism Cancer is an example.
12.4 Mutations and Gene Regulation