Menopause. Menopause Health screening of healthy postmenopausal women.

Slides:



Advertisements
Similar presentations
Endometrial polyps Dr Shaun Monagle MBBS 1991.
Advertisements

OPTIONAL LOGO HERE Prevalence of endometrial cancer in symptamatic women with thickened endometrium Dr Maheswari SRINIVASAN MRCOG SpR, Mrs Shagaf BAKOUR.
Diagnostic Techniques for Endometrial Cancer By:Sara Lotfiyan.
A significant increase in the incidence of endometrial cancer. This increased incidence of endometrial cancer has been widely interpreted to be a result.
King Abdul Aziz University Faculty Of Pharmacy
Endometrial Cancer Faina Linkov, PhD Research Assistant Professor University of Pittsburgh Cancer Institute.
Endometrial Cancer Screening for Cancer in Women.
District 1 ACOG Medical Student Teaching Module 2009
Asymptomatic Endometrial Thickening in Postmenopausal Patient Dr
POST MENOPAUSAL WOMAN RAGINI REDDY CONSULTANT GYNAECOLOGIST.
Abnormal Uterine Bleeding
Endometrial Hyperplasia
Post Menopausal Bleeding
Chapter 61 Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications 1.
Osteoporosis Dr. Lauren Phillips Sugar Land Women’s Health.
Treatment. Bisphosphonates Promotes bone formation and decreases bone resorption Mechanism of Action First line treatment for osteoporosis in both men.
 The term post menopause is applied to women who have not experienced a menstrual bleed for a minimum of 12 months, assuming that they do still have.
Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 75 Drugs Affecting Calcium Levels and Bone Mineralization.
Post-menopausal bleeding PV Dr Nasira Sabiha Dawood.
Menopause: The Journal of The North American Menopause Society
M E N O P A U S E King Khalid University Hospital Department of Obstetrics & Gynecology Course 481.
MENOPAUSE DR. AMEL EL-SAYED, FRCSC Assistant Professor & Consultant King Saud University King Khalid University Hospital.
Carcinoma Corpus Uteri
Medication Options H ealthPLACE/HOPE Program COPYRIGHT © 2002 Highmark Inc. All Rights Reserved. These materials may not be copied or otherwise reproduced.
How to survive your menopause David Griffiths Consultant Gynaecologist Christine Pearce Consultant Nurse 3 rd Sept 2014.
Who Cares?. Applied Physiology: Menopause Widmaier text p. 694 Onset ~ age 50 Irregular menstrual cycles Breasts and genital organs gradually atrophy.
Postmenopausal bleeding
Osteoporosis. Background ► The problem  Osteoporosis is common  Over 50% of women and 30-45% of men over age 50 have osteopenia/osteoporosis  White.
Breast Cancer Prevention Art or Science? Kristi McIntyre M.D. Texas Oncology 2005.
University Clinical Centre Maribor, Slovenia
Cancer, Exercise & Bone Health
Vaginal Bleeding in the Perimenopause (Age 35-50)
Tamoxifen associated changes
Malignant & Pre-malignant Diseases of the Endometrium Jose B Moran MD Assistant Professor III Section of Gynecologic Oncology Department of Obstetrics.
KARIMA SALAMA ENDOMETRIAL CANCER. Epidemiology Most common gynecological cancer in the developed countries, with an incidence of 12.9 per 100,000 women.
ABNORMAL UTERINE BLEEDING
Welcome To Our Presentation
HORMONE REPLACEMENT THERAPY (HRT) Evidence-based Guidelines Dr Mahdy El- Mazzahy Damietta general Hospital 7 th International Annual Congress “Alexandria”
Chapter ?? 23 Osteoporosis Nichols and Pavlovic C H A P T E R.
Dr. Ahmed jasim Ass.Prof.MBChB-DOG-FICMS COSULTANT OF GYN. & OBST. COSULTANT OF GYN. & OBST.
Date of download: 7/18/2016 Copyright © 2016 McGraw-Hill Education. All rights reserved. Chart for identifying appropriate candidates for postmenopausal.
M.D. Browning, M.D. ‘77.  Most Common Cancer of Female Reproductive System  60,000/year with 10,000 deaths  Normal Cells in the Endometrium.
Osteoporosis. Definitions: - - Osteoblasts: Fibroblasts essential for bone formation and mineralization of bone matrix - - Osteoclasts: Cells that break.
Malignant disease of the body of the uterus
Malignant disease of the body of the uterus
AROMATASE INHIBITORS.
SERMs Dr Sarvesh Singh Associate Professor
Postmenopausal bleeding
Changes before the change: Perimenopausal Bleeding
Endometrial hyperplasia
Post Menopausal Bleeding
Drugs Affecting Calcium Levels and Bone Mineralization
Copyright © 2015 by the American Osteopathic Association.
ENDOMETRIAL HYPERPLASIA
Malignant disease of the body of the uterus
The postmenopausal bleeding (PMB)
Changes before the change: Perimenopausal Bleeding
Health Science 1 Project
9/18/2018 OSTEOPOROSIS.
Chapter 61 Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications 1.
Uterine cancer Uterine mesenchymal neoplasms
Bone-Targeted Therapy in the Adjuvant Breast Cancer Setting
Osteoporosis Definition
Uterine Leiomyomas. Uterine Leiomyomas Most common benign uterine tumors Location :uterus ,cervix ,broad ligament Subserosal Intramural Submucosal.
Bone-Targeted Therapy in the Adjuvant Breast Cancer Setting
Chapter Drugs used for the treatment of osteoporosis
Hormone Replacement Therapy (HRT)
Management of Endometrial Hyperplasia D Hind Showman
(Relates to Chapter 64, “Focous on osteoperosis ,” in the textbook)
Presentation transcript:

Menopause

Health screening of healthy postmenopausal women

The impact of postmenopausal estrogen deprivation

Menopausal hormone therapy and the risk of breast cancer

Menopausal hormone therapy and the risk of cardiovascular

Preparation for menopausal hormone therapy

Choice of estrogen/progestin regimen

Other symptoms that respond to estrogen therapy

Use of Contraceptives during the menopausal transition

Stopping hormone therapy and tapering

Compounded bio-identical hormone therapy

Exercise role in prevention and treatment osteoporosis

Calcium/vitamin D supplementation in osteoporosis

Intensity of exercise

Fracture risk assessment

Candidates for treatment of osteoporosis and osteopenia in postmenopausal women

The use of bisphosphonates in postmenopausal women with osteoporosis

Contraindications/intolerance of bisphosphonates

Pretreatment evaluation of bisphosphonates therapy

Risk of bisphosphonate therapy in patient with osteoporosis

Combination therapy

When to initiate bisphosphonates

Fracture healing in patients already taking bisphosphonates

Guidelines for monitoring response to therapy

Bone mineral density stable or increased

Bone mineral density decreased or fracture during therapy

Parathyroid hormone/parathyroid hormone-related protein analog

Denosumab for osteoporosis

Selective estrogen receptor modulators (Raloxifene)

Calcitonin for osteoporosis

Isoflavones supplements

Risk factors of menopausal hotflashes

Duration of menopausal hotflashes

Clinical manifestations of menopausal hotflashes

Differential diagnosis of hotflashes

Menopausal hormone therapy in women with menopausal hotflashes

Bazedoxifene/conjugated estrogen for treatment of menopausal hotflashes

SSRIs/SNRIs for treatment of menopausal hotflashes

Gabapentin for treatment of menopausal hotflashes

Paroxetine for treatment of menopausal hotflashes

Clonidine for treatment of menopausal hotflashes

Depot medroxiprogesteron acetate for treatment of menopausal hotflashes

hotflashes in women with breast cancer

Plant based therapy for treatment of menopausal hotflashes

Acupuncture for treatment of menopausal hotflashes

Clonidine for treatment of menopausal hotflashes

Autoimmune endocrinopathies in women with premature menopause

Spontaneous ovulation in women with premature menopause

Role of estrogen, clomiphene, gonadotropin, glucocorticoid therapy in infertile women with POF

Approach to Management of women with POF

Contraception in women with premature menopause

Duration of therapy in women with premature menopause

Androgen replacement therapy in women with premature menopause

Etiology postmenopausal uterine bleeding

Risk factors endometrial cancer

Endometrial evaluation Endometrial biopsy Dilation and curettage Hysteroscopy Saline infusion sonohysterography Transvaginal ultrasound

Asymptomatic menopausal women with endometrial thickening

Asymptomatic menopausal women with fluid within the endometrial cavity

Endometrial thickening in women on hormone therapy

Endometrial thickening in women on tamoxifen

An ultrasound risk-scoring model for prediction of endometrial cancer in post-menopausal women

Endometrial hyperplasis: terminology and histologic class (2015, WHO)

Classification system Histologic category 2015 WHO Normal endometrium Hyperplasia without atypia (non-neoplastic) Atypical hyperplasia (neoplastic) Endometrial carcinoma 1994 WHO Simple hyperplasia without atypia Complex hyperplasia without atypia Simple Atypical hyperplasia (rare) Complex Atypical hyperplasia Endometrial intraepithelial neoplasia Benign endometrial hyperplasia Additional terms used in Proliferative endometrium Disordered proliferative endometrium Gland crowding

Management of proliferative endometrium

Management of nonatypical hyperplasia/benign endometrial hyperplasia (and some EIN)

Complex hyperplasia without atypia benign endometrial hyperplasia (some EIN)/gland crowding

Atypical hyperplasia/EIN

The end