Dichotomy between postprandial glucose and lipid profiles in adults with cystic fibrosis: A pilot study I. Hammana, L. Coderre, S. Potvin, M. Costa,

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Presentation transcript:

Dichotomy between postprandial glucose and lipid profiles in adults with cystic fibrosis: A pilot study I. Hammana, L. Coderre, S. Potvin, M. Costa, Y. Berthiaume, A. Lavoie, J.-L. Chiasson, E. Levy, R. Rabasa-Lhoret Journal of Cystic Fibrosis Volume 8, Issue 2, Pages 128-134 (March 2009) DOI: 10.1016/j.jcf.2008.11.002 Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Plasma glucose profile in response to a TM (A) and an OGTT (B) in CF patients and controls. CF-normal glucose tolerance (CF-NGT); CF-related diabetes (CFRD). *P<0.05 CFRD vs. Controls; ΔP<0.05 CFRD vs. NGT; ΨP<0.05 NGT vs. Controls. Journal of Cystic Fibrosis 2009 8, 128-134DOI: (10.1016/j.jcf.2008.11.002) Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 Total glucose area under the curve (AUC) of the OGTT and TM. ⁎P<0.005 TM vs OGTT; ΔP<0.0001 NGT vs Controls for TM and OGTT; €P<0.0001 CFRD vs Controls for the TM and OGTT; ¥P<0.0001 CFRD vs NGT for TM and OGTT. Journal of Cystic Fibrosis 2009 8, 128-134DOI: (10.1016/j.jcf.2008.11.002) Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions

Fig. 3 Insulin profile in response to a TM (A) and an OGTT (B) in CF patients and controls. CF-normal glucose tolerance (CF-NGT); CF-related diabetes (CFRD). Journal of Cystic Fibrosis 2009 8, 128-134DOI: (10.1016/j.jcf.2008.11.002) Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions

Fig. 4 Triglyceride levels in response to a TM (A) and an OGTT (B) in CF-patients and controls. CF-normal glucose tolerance (CF-NGT); CF-related diabetes (CFRD). *P<0.01 versus basal condition (time 0). Journal of Cystic Fibrosis 2009 8, 128-134DOI: (10.1016/j.jcf.2008.11.002) Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions

Fig. 5 FFA levels in response to a TM (A) and an OGTT (B) in CF patients and controls. CF-normal glucose tolerance (CF-NGT); CF-related diabetes (CFRD). *P<0.05 versus basal condition (time 0). Journal of Cystic Fibrosis 2009 8, 128-134DOI: (10.1016/j.jcf.2008.11.002) Copyright © 2008 European Cystic Fibrosis Society. Terms and Conditions