Protein Quality Control: On IPODs and Other JUNQ Katrin Bagola, Thomas Sommer  Current Biology  Volume 18, Issue 21, Pages R1019-R1021 (November 2008) DOI: 10.1016/j.cub.2008.09.036 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Quality control compartments in yeast or mammalian cells. The IPOD compartment harbors aggregated, non-ubiquitylated proteins and is localized at the cell periphery. JUNQ, which contains ubiquitylated polypeptides, is found in an indentation of the nucleus where it is associated with proteasomes. The previously described aggresome and ERAC exhibit JUNQ-related functions but differ in compartment architecture. Current Biology 2008 18, R1019-R1021DOI: (10.1016/j.cub.2008.09.036) Copyright © 2008 Elsevier Ltd Terms and Conditions