Lecture 5C 7 Oct. 2016 Lipids III

rheumatoid arthritis pathology diet ELIMINATION THERAPY  

Rheumatoid arthritis continued Elimination diet dong diet-simple foods (seafood, veggies, and rice while eliminating additives, preservatives, red meat, herbs, dairy products, spices, carbonated drinks and ethanol)  

Arthritis and diet continued Elimination therapy no difference between dong and placebo diets for RA patients-other dietary elimination studies have come up with the same thing role of diet in RA is controversial because existing studies do not give clear cut result

ARTHRITIS CONTINUED Functional foods fish-doesn’t work -no other proven examples of functional foods  

Arthritis continued Nutraceuticals evening primrose oil borage oil black currant oil fish oil

b) Eczema Pathology food allergy or RA associated diet solution-remove food allergen from diet for RA associated diet - no proven dietary approach known

Eczema continued functional foods fish-a problem no other proven functional food   nutraceuticals evening primrose oil borage oil black currant oil fish oil

Cancer pathology diet saturated fat does not cause cancer but promotes once it gets started- not conclusive but reduce saturated fat

Cancer continued Functional foods flax-lignans-SDG- secoisolariciresinol diglycoside   Nutraceuticals phytosterols

Obesity Pathology Diet -reduce total fat intake Functional foods   Functional foods Nutraceuticals

Dietary fat recommendations- p 154 increased oleic acid intake and low in saturated and trans fats, and cholesterol total fat-20-35 % of total energy intake-only above 30 % of total calories if consume increased amounts of oleic acid and with low saturated and trans fat intake(CFG) saturated fat-10 % of total energy intake maximum linoleic acid- 5-10 % of total energy intake-essential fatty acid alpha-linolenic acid- 0.6-1.2 % of daily calories- ALA is an essential fatty acid

Dietary fat recommendations cholesterol-300 mg /day max in persons not at risk of clinically significant atherosclerosis eat plenty of vegetables, fruit and grains

What is new in lipid research? Tilakavati Karupaiah and Kalyana Sundram Modulation of human postprandial lipemia by changing ratios of polyunsaturated to saturated (P/S) fatty acid content of blended dietary fats: a cross-over design with repeated measures Nutrition Journal 2013, 12:122 doi:10.1186/1475-2891-12-122

What is new in lipid research? Nutrition Journal 2013, 12:122 doi:10.1186/1475-2891-12-122 Prolonged post-prandial lipemia (elevated plasma triglyceride concentrations) poses significant risks for heart attack in terms of elevated plasma concentrations of chylomicron triglycerides and lowered HDL-c. Compared to higher polyunsaturated:saturated (P:S) fatty acid diets, a low P:S diet gave the best increase in post-prandial HDL-c levels but low dietary P:S ratios caused an upward trend (non-significant) in post-prandial total plasma triglyceride levels. So caution regarding P:S ratios until there are more definitive results!!