Premorbid Obesity and Mortality in Patients With Pancreatic Cancer: A Systematic Review and Meta-analysis  Kaustav Majumder, Arjun Gupta, Nivedita Arora,

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Presentation transcript:

Premorbid Obesity and Mortality in Patients With Pancreatic Cancer: A Systematic Review and Meta-analysis  Kaustav Majumder, Arjun Gupta, Nivedita Arora, Preet Paul Singh, Siddharth Singh  Clinical Gastroenterology and Hepatology  Volume 14, Issue 3, Pages 355-368.e2 (March 2016) DOI: 10.1016/j.cgh.2015.09.036 Copyright © 2016 AGA Institute Terms and Conditions

Figure 1 Flow sheet summarizing study identification and selection. OR, short of odds ratio; PaC, pancreatic cancer; RR, relative risk. Clinical Gastroenterology and Hepatology 2016 14, 355-368.e2DOI: (10.1016/j.cgh.2015.09.036) Copyright © 2016 AGA Institute Terms and Conditions

Figure 2 (A) Summary of maximally adjusted HR for association between premorbid BMI and pancreatic cancer–related mortality, comparing patients in the highest category of BMI with the lowest category. The size of the box corresponds to the weight of the given study. (B) Summary of maximally adjusted HR for association between premorbid BMI and pancreatic cancer–related mortality, comparing overweight (BMI 25.0–29.9 kg/m2) and obese (BMI ≥30 kg/m2) patients with normal BMI patients. The size of the box corresponds to the weight of the given study. (C) Summary of maximally adjusted HR for evaluation of dose-response relationship between premorbid BMI and pancreatic cancer–related mortality. The estimate represents mortality increase per 1 kg/m2 increase in BMI. SE, standard error. Clinical Gastroenterology and Hepatology 2016 14, 355-368.e2DOI: (10.1016/j.cgh.2015.09.036) Copyright © 2016 AGA Institute Terms and Conditions

Supplementary Figure 1 Funnel plot, showing no evidence of publication bias. SE, standard error. Clinical Gastroenterology and Hepatology 2016 14, 355-368.e2DOI: (10.1016/j.cgh.2015.09.036) Copyright © 2016 AGA Institute Terms and Conditions