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Nat. Rev. Endocrinol. doi:10.1038/nrendo.2016.15 Figure 2 Differential effects of daytime versus night time hypoglycaemia on cardiovascular risk Figure 2 | Differential effects of daytime versus night time hypoglycaemia on cardiovascular risk. Nocturnal hypoglycaemia is associated with more cardiac arrhythmias than what is observed during daytime hypoglycaemia. Hyperglycaemia was associated with an increased risk for VPB during the day but not overnight. HR, heart rate; IG, interstitial glucose; QTc, cardiac repolarization interval; VPB, ventricular premature beats. Umpierrez, G. & Korytkowski, M. (2015) Diabetic emergencies — ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia Nat. Rev. Endocrinol. doi:10.1038/nrendo.2016.15