Do now activity #2 What is the physiology of sebaceous glands? What is the physiology of hair? What is the physiology of nails? What is the pigment that gives skin its color? What are the cells that produce this pigment called? List all the types of sweat glands.

What is the treatment plan for the 3 different types of skin cancer? Essential Question: What is the treatment plan for the 3 different types of skin cancer? chapter 5-3: Skin cancer Learning Target describe the characteristics of the three types of skin cancer (basal cell carcinoma, squamous cell carcinoma, and melanoma).

announcements Chapter 1 Retake (>70%) Completed stamp sheet assignments Retake score will be permanent Class website will be updated today Refer to stamp sheet for list of assignments Quiz 1 scheduled for: Wednesday, 9/19/18 Quiz 2 scheduled for: Thursday, 9/20/18 Chapter 5 Test scheduled for: Tuesday, 9/25/18 Last Day to Stamp Chapter 5: Monday, 9/24/18

Available Extra Credit announcements Available Extra Credit OR Tissue/Pencil Box = 5 Point Class Pass (Limit 2 per student per chapter)

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overview Cancer is uncontrolled cell growth that produces a mass of cells called tumors

Most skin tumors are benign and do not metastasize (spread) overview Most skin tumors are benign and do not metastasize (spread)

overview A crucial risk factor for non-melanoma skin cancers is the disabling of the p53 gene

Newly developed skin lotions can fix damaged DNA overview Newly developed skin lotions can fix damaged DNA

Skin cancer The three major types of skin cancer are: Basal cell carcinoma Squamous cell carcinoma Melanoma

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Basal Cell Carcinoma Basal cell carcinoma is the least malignant & most common skin cancer Epidermal bottom layer cells (Stratum basale) divide rapidly and invade the dermis & hypodermis Slow growing and do not often metastasize Can be cured by surgical excision (cut out) in 99% of the cases

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Squamous Cell Carcinoma Squamous cell carcinoma arises from keratinocytes of a deep layer of the epidermis Arise most often on scalp, ears, and lower lip Grows rapidly and metastasizes if not removed Prognosis is good if treated by radiation therapy or removed surgically

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Melanoma Melanoma is cancer of melanocytes Is the most dangerous type of skin cancer because it is: Highly metastic (spreads fast) Resistant to chemotherapy

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Characteristics of melanoma Melanoma can be detected by using the ABCD Rule

Characteristics of melanoma A: Asymmetry Two side do not match B: Border Has indentations C: Color Has several colors D: Diameter Larger than 6 mm * Some also use E: Elevation