European Urology Oncology Validation of the Decipher Test for Predicting Distant Metastatic Recurrence in Men with High-risk Nonmetastatic Prostate Cancer 10 Years After Surgery  Thomas Van den Broeck, Lisa Moris, Thomas Gevaert, Lorenzo Tosco, Elien Smeets, Nick Fishbane, Yang Liu, Christine Helsen, Jennifer Margrave, Christine Buerki, Elai Davicioni, Hendrik Van Poppel, Wouter Everaerts, Sheila Weinmann, Robert Den, John Davis, Edward Schaeffer, R. Jeffrey Karnes, Frank Claessens, Steven Joniau  European Urology Oncology  DOI: 10.1016/j.euo.2018.12.007 Copyright © 2018 Terms and Conditions

Fig. 1 CONSORT diagram showing the study design and the patient selection process for the Leuven cohort. Bx=biopsy; EAU=European Association of Urology; PC=prostate cancer; PLND=pelvic lymph node dissection; PSA=prostate-specific antigen. European Urology Oncology DOI: (10.1016/j.euo.2018.12.007) Copyright © 2018 Terms and Conditions

Fig. 2 Decipher score distribution plots. (A) Decipher score distributions among cases and controls. Horizontal lines denote the median scores and interquartile range. Whiskers of the boxplot represent all of the values included. Dashed lines represent the cut points for the Decipher risk groups. (B) Decipher risk-group distributions among cases and controls. European Urology Oncology DOI: (10.1016/j.euo.2018.12.007) Copyright © 2018 Terms and Conditions

Fig. 3 Cumulative incidence analysis: incidence of metastatic recurrence stratified according to Decipher score groups. Time from radical prostatectomy (RP) to distant metastases (Mets), with time zero representing the date of surgery. European Urology Oncology DOI: (10.1016/j.euo.2018.12.007) Copyright © 2018 Terms and Conditions

European Urology Oncology DOI: (10.1016/j.euo.2018.12.007) Copyright © 2018 Terms and Conditions

European Urology Oncology DOI: (10.1016/j.euo.2018.12.007) Copyright © 2018 Terms and Conditions