Rosai-Dorfman disease with a concurrent mantle cell lymphoma

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Presentation transcript:

Rosai-Dorfman disease with a concurrent mantle cell lymphoma Alexandra Edelman, MD, Brittany Patterson, BS, Kristen Donovan, MD, Janine Malone, MD, Jeffrey Callen, MD JAAD Case Reports Volume 5, Issue 1, Pages 40-43 (January 2019) DOI: 10.1016/j.jdcr.2018.09.017 Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Patient observed initially (A) and 5 months after consolidation therapy (B). JAAD Case Reports 2019 5, 40-43DOI: (10.1016/j.jdcr.2018.09.017) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Biopsy findings show a diffuse infiltrate of mononuclear cells with abundant pale cytoplasm in the papillary dermis. B, On higher power, histiocytes with abundant cytoplasm and conspicuous nucleoli (red arrows) and emperiopolesis of lymphocytes and neutrophils (black arrows) are seen. C, S100+ staining of histiocytes. D, Higher-power view of S100+ histiocytes with negative staining of intracytoplasmic hematolymphoid cells (arrows). JAAD Case Reports 2019 5, 40-43DOI: (10.1016/j.jdcr.2018.09.017) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions