Association Between Pulmonary Mycobacterium Avium Complex Infection and Lung Cancer Leah Lande, MD, Donald D. Peterson, MD, Radhika Gogoi, MD, PhD, Gary.

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Association Between Pulmonary Mycobacterium Avium Complex Infection and Lung Cancer Leah Lande, MD, Donald D. Peterson, MD, Radhika Gogoi, MD, PhD, Gary Daum, MD, Kate Stampler, DO, Rebecca Kwait, BSN, RN, Christine Yankowski, MHS, DO, Kate Hauler, Joshua Danley, DO, Kristen Sawicki, BA, JD, Janet Sawicki, PhD Journal of Thoracic Oncology Volume 7, Issue 9, Pages 1345-1351 (September 2012) DOI: 10.1097/JTO.0b013e31825abd49 Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Total number of cases of pulmonary infection caused by MAC and TB at Lankenau Medical Center, 1996–2010. MAC, Mycobacterium avium complex; TB, tuberculosis. Journal of Thoracic Oncology 2012 7, 1345-1351DOI: (10.1097/JTO.0b013e31825abd49) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 A, Distribution of different histologic subtypes of lung cancer in female patients with and without MAC infection, and (B) in male patients with and without MAC infection. MAC, Mycobacterium avium complex. Journal of Thoracic Oncology 2012 7, 1345-1351DOI: (10.1097/JTO.0b013e31825abd49) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 A, Tumor location in patients with squamous cell carcinoma with and without pulmonary MAC infection. B, Computed tomography scan of study patient with MAC and peripheral squamous cell carcinoma. Short arrow indicates location of squamous cell carcinoma. Long arrows indicate areas of bronchiolitis and nodular bronchiectasis typical of MAC infection. MAC, Mycobacterium avium complex. Journal of Thoracic Oncology 2012 7, 1345-1351DOI: (10.1097/JTO.0b013e31825abd49) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

Figure 4 Lung pathology specimen of study patient depicting squamous cell carcinoma (upper arrow) adjacent to a region of granulomatous inflammation typical of MAC infection (lower arrow). MAC, Mycobacterium avium complex. Journal of Thoracic Oncology 2012 7, 1345-1351DOI: (10.1097/JTO.0b013e31825abd49) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions