Reconciling Aging With HIV

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Presentation transcript:

Reconciling Aging With HIV

Introduction

How Is the Epidemiology of HIV Changing in the Context of Aging?

People Living With Diagnosed HIV, 2015

Noncommunicable Comorbidities in PLWHIV ≥ 45 Years Old

POPPY Study: Effects of Aging on Clinical Outcomes of PLWHIV

Accelerated vs Accentuated Aging

Cardiovascular Risk Factors for PLWHIV

Shift in the Epidemiology of HIV-Associated Malignancy

Incidence of NADCs in PLWHIV > 65 Years Old

A Higher Rate of NADCs in Persons With AIDS

NADC-Related Mortality Is Increasing

Why a Shift Toward NADCs?

Global Burden of Disease: Trends in Age-Standardized Mean BMI

Higher Comorbidity Burden Results in Frailty

HIV and Malignancy: Drug-Drug Interaction (DDI) Considerations

Reducing the Burden of Polypharmacy

Risk Factors for Malignancy

Screening for NADMs: HCC

Screening for NADMs: Lung Cancer

Screening for NADMs: Anal Cancer

Liver-Related Diseases as a Primary Cause of Death in PLWHIV

Persistent Increase in HCC Despite HIV Control

Concluding Remarks

Abbreviations

Abbreviations (cont)