Charles M. Rudin, MD, PhD, Alexander Drilon, MD, J.T. Poirier, PhD

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Presentation transcript:

RET Mutations in Neuroendocrine Tumors: Including Small-Cell Lung Cancer Charles M. Rudin, MD, PhD, Alexander Drilon, MD, J.T. Poirier, PhD Journal of Thoracic Oncology Volume 9, Issue 9, Pages 1240-1242 (September 2014) DOI: 10.1097/JTO.0000000000000301 Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Reported frequencies of gene alterations in RET across multiple common solid tumor types. Data are derived from cBioPortal (www.cbioportal.org). The primary sources of these datasets are from the Cancer Genome Atlas Consortium (TCGA); esophagus cancer was not included in TCGA, and data is from the Broad Institute. Data on small-cell lung cancer, also not in TCGA, are derived from two genome profiling reports, references 13 (Clinical Lung Cancer Genome Project [CLCGP]) and 14 (Johns Hopkins University [JHU]). Adeno, adenocarcinoma; SC, small cell; Squ, squamous; ACC, adrenocortical carcinoma; pRCC, papillary renal cell carcinoma; GBM, glioblastoma. Journal of Thoracic Oncology 2014 9, 1240-1242DOI: (10.1097/JTO.0000000000000301) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions