Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial 

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Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial  Kate E Duhig, MRCP, Jenny Myers, PhD, Paul T Seed, CStat, Jenie Sparkes, BSc, Jessica Lowe, FRANZCOG, Rachael M Hunter, MSc, Prof Andrew H Shennan, MD, Prof Lucy C Chappell, PhD Rachna Bahl, Gabrielle Bambridge, Sonia Barnfield, Jo Ficquet, Carolyn Gill, Joanna Girling, Kate Harding, Asma Khalil, Andrew Sharp, Nigel Simpson, Derek Tuffnell Kate E Duhig, MRCP, Jenny Myers, PhD, Paul T Seed, CStat, Jenie Sparkes, BSc, Jessica Lowe, FRANZCOG, Rachael M Hunter, MSc, Prof Andrew H Shennan, MD, Prof Lucy C Chappell, PhD Rachna Bahl, Gabrielle Bambridge, Sonia Barnfield, Jo Ficquet, Carolyn Gill, Joanna Girling, Kate Harding, Asma Khalil, Andrew Sharp, Nigel Simpson, Derek Tuffnell  The Lancet  DOI: 10.1016/S0140-6736(18)33212-4 Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Trial profile The Lancet DOI: (10.1016/S0140-6736(18)33212-4) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Proportion of women diagnosed with pre-eclampsia when revealing versus concealing circulating placental growth factor concentrations from clinicians, over days (A) and weeks (B) Data are mixed-effects log-normal regression curves. The Lancet DOI: (10.1016/S0140-6736(18)33212-4) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions