Bedside detection of awareness in the vegetative state: a cohort study

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Bedside detection of awareness in the vegetative state: a cohort study Dr Damian Cruse, PhD, Srivas Chennu, PhD, Camille Chatelle, MSc, Tristan A Bekinschtein, PhD, Davinia Fernández-Espejo, PhD, Prof John D Pickard, MD, Prof Steven Laureys, MD, Prof Adrian M Owen, PhD The Lancet Volume 378, Issue 9809, Pages 2088-2094 (December 2011) DOI: 10.1016/S0140-6736(11)61224-5 Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 1 Scalp locations of the 25 electrodes contributing to the classification analyses The Lancet 2011 378, 2088-2094DOI: (10.1016/S0140-6736(11)61224-5) Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 2 Modulation of the appropriate frequency bands of the EEG signal that are associated with motor imagery in three patients and one healthy control participant Maps show the scalp distribution of the feature (timepoint × frequency band) with the highest absolute coefficient value from one training run of the cross-validation procedure. Red colours show coefficient values greater than zero. Blue colours show values less than zero. When the scalp distributions of data for the classification procedure are plotted, the neurophysiological basis of the positive EEG outcome—with clear foci over the hand and toe motor areas—are formally identical when compared between a healthy control participant and the three patients in the vegetative state who significantly followed commands with this EEG task. The Lancet 2011 378, 2088-2094DOI: (10.1016/S0140-6736(11)61224-5) Copyright © 2011 Elsevier Ltd Terms and Conditions