Epidermal Growth Factor Receptor Mutation and p53 Overexpression during the Multistage Progression of Small Adenocarcinoma of the Lung Seol Bong Yoo,

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Epidermal Growth Factor Receptor Mutation and p53 Overexpression during the Multistage Progression of Small Adenocarcinoma of the Lung Seol Bong Yoo, MD, Jin-Haeng Chung, MD, PhD, Hyun Ju Lee, MD, Choon-Taek Lee, MD, PhD, Sanghoon Jheon, MD, PhD, Sook Whan Sung, MD, PhD Journal of Thoracic Oncology Volume 5, Issue 7, Pages 964-969 (July 2010) DOI: 10.1097/JTO.0b013e3181dd15c0 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Representative histologic feature for lesions. A, Atypical cuboidal cells resembled type II pneumocyte with little nuclear pleomorphism in atypical adenomatous hyperplasia (AAH). B, Atypical tall columnar cells lining with intact underlying alveolar space in bronchioloalveolar carcinoma (BAC). C, Invasive adenocarcinoma (ADC) with central fibrosis. Journal of Thoracic Oncology 2010 5, 964-969DOI: (10.1097/JTO.0b013e3181dd15c0) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions