M. Unemo, V. Vorobieva, N. Firsova, T. Ababkova, I. Leniv, B. C

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Neisseria gonorrhoeae population in Arkhangelsk, Russia: phenotypic and genotypic heterogeneity M. Unemo, V. Vorobieva, N. Firsova, T. Ababkova, I. Leniv, B.C. Haldorsen, H. Fredlund, V. Skogen Clinical Microbiology and Infection Volume 13, Issue 9, Pages 873-878 (September 2007) DOI: 10.1111/j.1469-0691.2007.01764.x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Neighbour-joining phylogenetic tree describing the evolutionary relationships of entire porB gene sequences (993 unambiguously aligned nucleotides), encoding mature PorB, of Neisseria gonorrhoeae isolates (n = 76) cultured in Arkhangelsk, Russia, during 2004. The most diverse porB1a sequence, i.e., from the isolate characterised as IA-1.2, ST1538, was used to root the tree. The length of the branch dividing the PorB1a (WI) and PorB1b (WII/III) isolates has been reduced by a factor of eight. The serovar and N. gonorrhoeae multi-antigen sequence typing (NG-MAST) sequence type (ST) of each isolate is indicated. In cases of several isolates with an identical serovar and ST, these are indicated as (n = x); *denotes an ST that has not been identified previously. Clinical Microbiology and Infection 2007 13, 873-878DOI: (10.1111/j.1469-0691.2007.01764.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Pie chart depicting the percentages of different Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST) sequence types (STs) identified among N. gonorrhoeae isolates (n = 76) cultured in Arkhangelsk, Russia, during 2004. The serovars identified within each ST and among the isolates displaying unique STs are described in parentheses; *denotes an ST that has not been identified previously. aAmong the unique STs, 89% (25/28) have not been identified previously. Clinical Microbiology and Infection 2007 13, 873-878DOI: (10.1111/j.1469-0691.2007.01764.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions