Measurements of metastatic renal cell tumours as determined by diffusion weighted imaging or computed tomography are in close agreement, a pilot study 

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Measurements of metastatic renal cell tumours as determined by diffusion weighted imaging or computed tomography are in close agreement, a pilot study  J. Farnebo, C. Suzuki, R. Vargas-Paris, P. Sandström, L. Blomqvist  European Journal of Radiology Open  Volume 4, Pages 45-49 (January 2017) DOI: 10.1016/j.ejro.2017.03.003 Copyright © 2017 The Authors Terms and Conditions

Fig. 1 Experimental flow-chart. CT and DWI examinations are performed before and after treatment. All 20 examinations (ten CT and ten DWI) were randomly presented to two radiologists who independently identified and measured up to ten tumour lesions. Data was collected and analysed by a third radiologist. European Journal of Radiology Open 2017 4, 45-49DOI: (10.1016/j.ejro.2017.03.003) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 Distribution of metastases identified by the two different reviewers labelled A and B. Reviewer B identified no lesion in the liver on DWI and reviewer A identified no peritoneal carcinosis lesion on CT. European Journal of Radiology Open 2017 4, 45-49DOI: (10.1016/j.ejro.2017.03.003) Copyright © 2017 The Authors Terms and Conditions

Fig. 3 Box-plot diagram of the size of target lesions as assessed by DWI or CT prior to and after 3 months of treatment. The line within the box represents the median value. The Wilcoxon signed rank test reveal significant differences in lesion dimension by either DWI or CT. European Journal of Radiology Open 2017 4, 45-49DOI: (10.1016/j.ejro.2017.03.003) Copyright © 2017 The Authors Terms and Conditions

Fig. 4 Bland-Altman plots illustrating the agreement between DWI and CT measurements both pre- and post-treatment. The lines represent means and 95% confidence intervals. Symbols represent the metastatic location (green triangles are lymph node, blue circles are pulmonary, yellow cubes are pleural, pink circles are intramuscular and brown triangles are peritoneal). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) European Journal of Radiology Open 2017 4, 45-49DOI: (10.1016/j.ejro.2017.03.003) Copyright © 2017 The Authors Terms and Conditions

Fig. 5 Two examples of different disparity between CT and DWI. A represents a pleural lesion pre-treatment and B a pulmonary lesion post-treatment. European Journal of Radiology Open 2017 4, 45-49DOI: (10.1016/j.ejro.2017.03.003) Copyright © 2017 The Authors Terms and Conditions