Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction J.R. Sneyd, J.A. Langton, L.G. Allan,

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Presentation transcript:

Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction J.R. Sneyd, J.A. Langton, L.G. Allan, J.E. Peacock, D.J. Rowbotham British Journal of Anaesthesia Volume 98, Issue 5, Pages 672-676 (April 2007) DOI: 10.1093/bja/aem075 Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 1 Verbal rating scale (VRS) scores in patients receiving placebo, GR79236 4 µg kg−1, GR79236 10 µg kg−1, or diclofenac 50 mg. Patients were asked to rate their pain as intolerable, severe, moderate, mild, or none. Times are minutes after commencing a 15-min infusion of study drug after patients had reported moderate pain or worse. Data are numbers of patients at each time point; patients requesting rescue analgesia were withdrawn from the study at that time. British Journal of Anaesthesia 2007 98, 672-676DOI: (10.1093/bja/aem075) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 2 Visual analogue scale (VAS) scores in patients receiving placebo, GR79236 4 µg kg−1, GR79236 10 µg kg−1, or diclofenac 50 mg. Times are minutes after commencing a 15-min infusion of study drug after patients had reported moderate pain or worse. Data are presented using ‘Last Observation Carried Forward’ where for patients receiving rescue or additional medication the worst score of baseline or last observation is carried forward. Means and sd, for clarity, sd is only presented for two treatment groups. British Journal of Anaesthesia 2007 98, 672-676DOI: (10.1093/bja/aem075) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions