Prevalence of Streptococcus pneumoniae isolates bearing macrolide resistance genes in association with integrase genes of conjugative transposons in Japan 

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Prevalence of Streptococcus pneumoniae isolates bearing macrolide resistance genes in association with integrase genes of conjugative transposons in Japan  T. Shiojima, Y. Fujiki, H. Sagai, S. Iyobe, A. Morikawa  Clinical Microbiology and Infection  Volume 11, Issue 10, Pages 808-813 (October 2005) DOI: 10.1111/j.1469-0691.2005.01232.x Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Examples of amplicons obtained following specific PCRs for detection of drug resistance and Int-Tn genes. Lanes: M, size marker; 1, mef(A), 402 bp; 2, erm(B), 224 bp; 3, Int-Tn1545, 742 bp, and tet(M), 377 bp; 4, Int-Tn5252, 877 bp. Clinical Microbiology and Infection 2005 11, 808-813DOI: (10.1111/j.1469-0691.2005.01232.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Distribution of the erm(B) and mef(A) macrolide resistance genes according to MICs of various antibiotics. Clinical Microbiology and Infection 2005 11, 808-813DOI: (10.1111/j.1469-0691.2005.01232.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions