Baseline Kidney Function as Predictor of Mortality and Kidney Disease Progression in HIV-Positive Patients Fowzia Ibrahim, MSc, Lisa Hamzah, MRCP, Rachael.

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Baseline Kidney Function as Predictor of Mortality and Kidney Disease Progression in HIV-Positive Patients Fowzia Ibrahim, MSc, Lisa Hamzah, MRCP, Rachael Jones, MRCP, Dorothea Nitsch, MD, MSc, Caroline Sabin, PhD, Frank A. Post, MD, PhD American Journal of Kidney Diseases Volume 60, Issue 4, Pages 539-547 (October 2012) DOI: 10.1053/j.ajkd.2012.03.006 Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Disposition of patients for the all-cause mortality and chronic kidney disease progression analyses. Abbreviations: CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate. American Journal of Kidney Diseases 2012 60, 539-547DOI: (10.1053/j.ajkd.2012.03.006) Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality and estimated glomerular filtration rate (eGFR) categories according to spline. Data were adjusted for age, sex, ethnicity, risk group, and years since entry into the cohort as fixed covariates and CD4 cell count, HIV (human immunodeficiency virus) RNA level, combination antiretroviral therapy use, AIDS, and hepatitis B surface antigen and hepatitis C antibody status as time-updated covariates. The diamond symbol represents the reference point of eGFR of 95 mL/min/1.73 m2 (knots at eGFRs of 45, 60, 75, 90, and 105 mL/min/1.73 m2). American Journal of Kidney Diseases 2012 60, 539-547DOI: (10.1053/j.ajkd.2012.03.006) Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions