Ovarian endomyometrioma with atypias: description of a case Gian Franco Zannoni, M.D., Valerio Gaetano Vellone, M.D., Guido Fadda, M.D., Massimiliano Guerriero, M.D., Arnaldo Carbone, M.D.  Fertility and Sterility  Volume 88, Issue 5, Pages 1438.e15-1438.e17 (November 2007) DOI: 10.1016/j.fertnstert.2007.01.049 Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Gross appearance of endomyometrioma: thick-walled cystic mass filled by red-brownish, chocolate-like material. (B) A thick muscular wall and a cavity lined by columnar epithelium associated with endometrial stroma are seen with the microscope (hematoxylin-eosin; original magnification, ×100). (C) Area with lining composed of atypical cells. Cells show abnormal nucleus and eosinophilic cytoplasm. Several hemosiderin-laden macrophages are present between lining and muscular wall (hematoxylin-eosin; original magnification, ×200). (D) Spindle cells within the wall are positive for caldesmon (smooth muscle cells) (labeled streptavidin biotin peroxidase method; original magnification, ×200). Zannoni. Ovarian endomyometrioma with atypias. Fertil Steril 2007. Fertility and Sterility 2007 88, 1438.e15-1438.e17DOI: (10.1016/j.fertnstert.2007.01.049) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions