Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study by Clare J Taylor, Andrea K Roalfe, Rachel Iles, FD Richard.

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Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study by Clare J Taylor, Andrea K Roalfe, Rachel Iles, FD Richard Hobbs, , P Barton, J Deeks, D McCahon, MR Cowie, G Sutton, RC Davis, J Mant, T McDonagh, and L Tait BJGP Volume 67(655):e94-e102 January 26, 2017 ©2017 by British Journal of General Practice

Flow diagram to show number of participants in REFER study. Flow diagram to show number of participants in REFER study. Step 1 = clinical info +ECG+echo. Step 2 = CDR variables. Step 3 = NT–proBNP result. CDR = clinical decision rule. DNA = did not attend. NT-proBNP = N-Terminal pro-B type natriuretic peptide levels. Clare J Taylor et al. Br J Gen Pract 2017;67:e94-e102 ©2017 by British Journal of General Practice

Receiver operating characteristic curves of CDR+NT-proBNP or NT-proBNP alone for predicting heart failure. Receiver operating characteristic curves of CDR+NT-proBNP or NT-proBNP alone for predicting heart failure. CDR = clinical decision rule. NT-proBNP = N-Terminal pro-B type natriuretic peptide levels. Clare J Taylor et al. Br J Gen Pract 2017;67:e94-e102 ©2017 by British Journal of General Practice