High-molecular-weight adiponectin is inversely associated with sympathetic activity in polycystic ovary syndrome Soulmaz Shorakae, M.D., Sally K. Abell,

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Presentation transcript:

High-molecular-weight adiponectin is inversely associated with sympathetic activity in polycystic ovary syndrome Soulmaz Shorakae, M.D., Sally K. Abell, M.B.B.S., Danielle S. Hiam, B.Ex.S.S.(Hons), Elisabeth A. Lambert, Ph.D., Nina Eikelis, Ph.D., Eveline Jona, M.D., Carolina Ika Sari, B.S., Nigel K. Stepto, Ph.D., Gavin W. Lambert, Ph.D., Barbora de Courten, Ph.D., Helena J. Teede, Ph.D. Fertility and Sterility Volume 109, Issue 3, Pages 532-539 (March 2018) DOI: 10.1016/j.fertnstert.2017.11.020 Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Burst frequency, (B) high-molecular-weight (HMW) adiponectin, (C) leptin, and (D) HMW adiponectin to leptin ratio (ALR) in women with polycystic ovary syndrome (PCOS) versus control women. ∗ Adjusted P=.047, ∗∗ adjusted P=.05. Fertility and Sterility 2018 109, 532-539DOI: (10.1016/j.fertnstert.2017.11.020) Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Correlation of high-molecular-weight (HMW) adiponectin with (A) burst frequency (r=−0.3 [95% CI −0.6, −0.001], P=.049) and (B) sex hormone-binding globulin (SHBG) (r= 0.5 [95% CI 0.2, 0.7, P<.001) in women with polycystic ovary syndrome (PCOS). Fertility and Sterility 2018 109, 532-539DOI: (10.1016/j.fertnstert.2017.11.020) Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions