Review JEOPARDY! History DNA structure Replication Transcription Translation $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500

$100 Who is Maurice Wilkins, Francis Crick, and James Watson? History These 3 individuals won the Nobel Prize in 1962 for their discoveries concerning the molecular structure of nucleic acids in DNA and its significance for information transfer. Who is Maurice Wilkins, Francis Crick, and James Watson? Jeopardy Menu

History $200 In what year did Watson and Crick publish their findings for the structure of DNA? What is 1953? Jeopardy Menu

History $300 This scientist produced an x-ray crystallography image that lead to the structure of DNA . Who is Rosalind Franklin? Jeopardy Menu

$400 Photo 51 revealed _____& _______in regards to the DNA molecule History Photo 51 revealed _____& _______in regards to the DNA molecule What is helical shape and diameter of the molecule? Jeopardy Menu

$500 It was over these 13 years that Human Genome was first sequenced. History $500 It was over these 13 years that Human Genome was first sequenced. What is 1990-2003? Jeopardy Menu

$100 DNA’s backbone consists of these two components (be specific). What are deoxyribose sugar and a phosphate group? Jeopardy Menu

$200 The sequence of these 4 bases determine our genetic code. DNA $200 The sequence of these 4 bases determine our genetic code. What are adenine, guanine, cytosine and thymine? Jeopardy Menu

$300 DNA This bond occurs between the 3’ carbon sugar of one nucleotide and the phosphate group of another nucleotide. What is phosphodiester bond? Jeopardy Menu

$400 DNA These two elements are attracted to each other creating two hydrogen bonds between adenine and thymine. Also, why is the phosphate group located on the outside of the molecule? What are hydrogen (slightly positive) and nitrogen (slightly negative)? What is hydrophilic? Jeopardy Menu

$500 DNA This is another name for the double ring nitrogenous bases (also include the names of each double ring). What are Purines (adenine and guanine)? Jeopardy Menu

Replication $100 This is the enzyme that breaks the hydrogen bonds between the two DNA parent strands. What is helicase? Jeopardy Menu

$200 This is the enzyme used to elongate a strand of DNA. Replication $200 This is the enzyme used to elongate a strand of DNA. What is DNA polymerase III? Jeopardy Menu

Replication $300 This information lead to the conclusion that purines must pair with pyrimidines and this lead to complementary base pairing and that DNA had a mechanism for replicating. What is the width of 20 Angstroms (determined by x-ray crystallography? Jeopardy Menu

$400 Replication The basis for the difference in how the leading and lagging strand are synthesized. What is DNA polymerase can only add new nucleotides to the 3’ end of a growing strand (thus it goes in the 5’ 3’ direction only)? Jeopardy Menu

$500 Replication A biochemist isolated, purified, and combined in a test tube a variety of molecules needed for DNA replication. When she added some DNA to the mixture replication occurred but each DNA molecule consisted of a normal strand paired with numerous segments of DNA a few hundred nucleotides long. This is the enzyme she forgot in her experiment. What is DNA ligase? Jeopardy Menu

$100 This is the main purpose of transcription. What is copying a gene from DNA to an mRNA strand? Jeopardy Menu

$200 This DNA template 3’ AATGCAT 5’ codes for this mRNA sequence. Transcription $200 This DNA template 3’ AATGCAT 5’ codes for this mRNA sequence. What is 5’ UUACGUA 3’? Jeopardy Menu

$300 This enzyme catalyzes the linkage between ribonucleotides. Transcription This enzyme catalyzes the linkage between ribonucleotides. What is RNA polymerase? Jeopardy Menu

$400 Transcription In order for transcription to occur, there has to be a specific recognition sequence. What is the promoter? Jeopardy Menu

$500 Transcription DAILY DOUBLE! Jeopardy Menu

Transcription $500 Including these three steps in transcription and before the mRNA leaves the nucleus these are removed . What is initiation, elongation, and termination? What are introns? Jeopardy Menu

$100 The structure of tRNA has two important features. Translation The structure of tRNA has two important features. What is the anticodon and the site for the amino acid? Jeopardy Menu

$200 This organelle is primarily responsible for protein synthesis. Translation This organelle is primarily responsible for protein synthesis. What are ribosomes? Jeopardy Menu

$300 The P site of a ribosome is where this occurs. Translation The P site of a ribosome is where this occurs. What is holding the tRNA containing the growing polypeptide chain? Jeopardy Menu

$400 Translation This specific mutation could result in a much shorter polypeptide chain. What is a nonsense base substitution? Jeopardy Menu

$500 Translation This is the first amino acid inserted into a new polypeptide chain. What is methionine? Jeopardy Menu