Metabolic response by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). a) FDG PET/CT for patient 2 at baseline (pre-therapy) and at 6 and 12 months of B-cell depletion (post-therapy). b) FDG PET/CT for patient 3 at b... Metabolic response by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). a) FDG PET/CT for patient 2 at baseline (pre-therapy) and at 6 and 12 months of B-cell depletion (post-therapy). b) FDG PET/CT for patient 3 at baseline (pre-therapy) and 7 months after B-cell depletion (post-therapy). MIP: maximum intensity projection; VOI: volume of interest; SUVmax: maximum standardised uptake value; MTV: metabolic tumour volume; TLG: total lesion glycolysis. Reproduced from [9] with permission from the publisher. Ioannis Vogiatzis et al. ERJ Open Res 2015;1:00002-2015 ©2015 by European Respiratory Society